The paper presents two observations made incidental to a series of unsuccessful experiments which were designed to study individual variation of response to stimuli intended to induce airsickness. The first observation suggests that capsules containing 50 mg. 1-methionine and 50 mg. pyridoxine, when administered initially and midway during a 4-hour flight, have a limited ability to protect human volunteers against motion sickness. The second observation identifies a structural similarity between the therapeutically effective antimotion sickness agents, neurochemical transmitters, and the peptide linkage.